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Untitled - Asian Journal of Andrology [PDF]
Transcript. 1 With the abbreviation of Asian Journal of Andrology"AJA" being the basic design element, a strong masculine body structure is created by traditional Chinese calligraphy. The man covering the blue globe symbolizes the consistent tenet of AJALocated in Asia, Facing the World. Asian Journal of Andrology, with this fresh image, is determined to create a brand new chapter …
Effect of ibrutinib with R-CHOP chemotherapy in genetic
Dec 13, 2021 · Analysis of biopsies from Phoenix trial patients revealed three previously characterized genetic subtypes of DLBCL: MCD, BN2, and N1. The 3-year event-free survival of younger patients (age ≤60 years) treated with ibrutinib plus R-CHOP was 100% in the MCD and N1 subtypes while the survival of patients with these subtypes treated with R-CHOP ...
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RNF31 - E3 ubiquitin-protein ligase RNF31
Dec 01, 2001 · E3 ubiquitin-protein ligase component of the LUBAC complex which conjugates linear ('Met-1'-linked) polyubiquitin chains to substrates and plays a key role in NF-kappa-B activation and regulation of inflammation (PubMed:17006537, PubMed:19136968, PubMed:20005846, PubMed:21455173, PubMed:21455180, PubMed:21455181, …
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Approaches to deformable physical sensors: Electronic
Oct 01, 2021 · Abstract. For the past two decades, the researches on stretchable physical sensors have made great technological advances, and have been applied to various applications such as electronic skin for robots, haptic devices, bionics, and wearable/implantable healthcare sensors, etc. The deformable physical sensors have been investigated in two ...
Global characterization of macrophage polarization
Nov 02, 2021 · He et al. provide a detailed characterization of dynamic temporal changes in cell signaling and metabolism during macrophage polarization by using quantitative time-course proteomics and phosphoproteomics and identify pharmacologic inhibitors of M2-type macrophage polarization. These data uncover a critical role of MEK/ERK signaling for …
The methyltransferase METTL3 negatively regulates
Dec 10, 2021 · The samples were derived from the same experiment and the gels were processed in parallel. e, f Cd36 or Ccl2 luciferase reporter plasmids were co-transfected with METTL3, D395A, or empty ...
3-hydroxy-L-kynurenamine is an immunomodulatory biogenic
Jul 21, 2021 · 3-hydroxy-L-kynurenamine (3-HKA) is a metabolite deriving from a lateral pathway of tryptophan catabolism. Here the authors identify 3-HKA as a biogenic amine and show it has anti-inflammatory ...
Cichoric Acid Ameliorates Monosodium Urate-Induced
Jan 07, 2021 · Gouty arthritis is characterized by the deposition of monosodium urate (MSU) within synovial joints and tissues due to increased urate concentrations. Here, we elucidated the role of the natural compound cichoric acid (CA) on the MSU crystal-stimulated inflammatory response. The THP-1-derived macrophages (THP-Ms) were pretreated with CA and then …
Diseases » NF-kB Transcription Factors
Diseases. NF-kB DISEASES. On this page are listed several diseases in which activation of NF-kB has been implicated. For general reviews on the role of NF-kB in disease, see Aradhya & Nelson (2001), Kumar et al (2004), Yamamoto & Gaynor (2002) or Baldwin (2001). For specific diseases see the listed references, which can be found either on this site (under References) or at …
Proceedings of the 27th European Paediatric Rheumatology
O1 Long-term efficacy and safety of canakinumab in patients with mevalonate kinase deficiency: results from the randomized phase 3 cluster trial J. Jeyaratnam1, A. Simon2, I. Calvo3, T. Constantin4, A. Shcherbina5, M. Hofer6, M. Gattorno7, A ...
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Banning open carry of unloaded handguns decreases firearm
Background Since 1967, in California it has been illegal to openly carry a loaded firearm in public except when engaged in hunting or law enforcement. However, beginning January 1, 2012, public open carry of unloaded handguns also became illegal. Fatal and non-fatal (NF) firearm injuries were examined before and after adoption of the 2012 ban to quantify the effect of the new law …
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Interleukin 1β-mediated HOXC10 Overexpression Promotes
Feb 19, 2020 · (C-F) Knockdown of HOXC10 inhibited IL-1β-mediated HCC metastasis. (C) Bioluminescence images, metastasis incidence, and number of lung metastasis foci of the indicated groups of nude mice are shown. (D) Bioluminescence signals. (E) Overall survival. (F) Representative HE staining of lung tissues from the different groups is shown.
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Ginseng Nutritional Components and Functional Factors [1st
Functional Foods and Nutraceuticals: Bioactive Components, Formulations and Innovations [1st ed.] 9783030423186, 9783030423193. Functional foods and nutraceuticals are food products that naturally offer or have been modified to offer additional hea
